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Pregnenolone: A Youthful Mind
Pregnenolone, a natural hormone in our bodies, acts as a catalyst for other hormones such as DHEA (dehydroepiandrosterone) and progesterone. Pregnenolone is seen as being an important factor in increasingly mental acuity and memory.
How Pregnenolone Works
While all the ways pregnenolone functions in our body are not readily understood, its suggested role is to serve as the starter for the other hormones. It is often called the mother of the steroids.
In a study of rats and pregnenolone's effect on their nervous system, the hormone was proven to have substantial enhancement effects on memory. In another study a different group of rats, whose spinal cords were deliberately injured, received a combination hormone therapy. Along with pregnenolone the rats were given indomethacin, and anti-inflammatory medicine as well as bacterial lipopolysaccharide to promote nerve function recovery. The combination of the three supplements was highly effective in comparison with the ingestion of one or two of the three hormones. Pregnenolone human studies have yet to be done on spinal cord injury patients.
Clearer Thinking
Although not proven, the scientific suggestion has been made that pregnenolone can help the neuroendocrine system in our bodies cope with stress. One study conducted of airplane pilots indicated a significant stress reduction as a result of a daily 25 mg dose. These pilots experienced no adverse side effects from the pregnenolone.
A study of people suffering from depression showed a lower than normal dosage of pregnenolone in the fluid around the brain, suggesting ingestion of pregnenolone for anti-depressant effects.
Human studies also determined that pregnenolone, given in 1 mg daily dosage, improved the quality of sleep for healthy men between the ages of 20 and 30. It also decreased their intermittent periods of wakefulness.
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